The causes of soreness and swelling in thighs are more common, such as muscle strain, trauma, neurological diseases, lumbar disc herniation, lumbar spinal stenosis, and lower limb vascular diseases, etc. Specific analysis is needed before taking the corresponding treatment. 1, muscle strain: If patients have recently overworked for a long time, pulling and stimulating the legs, too much strenuous exercise, or when muscular dystrophy, it will make the body’s creatine kinase secretion Excessive high, muscle accumulation of a large number of lactic acid, resulting in local symptoms of soreness and pain; 2, trauma: when the patient’s legs by trauma, due to damage to muscle tissue, local tissue fluid exudation, resulting in inflammation and edema, may also cause symptoms of thigh soreness and pain; 3, neurological diseases: such as muscle strength, muscle tone, tendon reflex abnormalities, there will be local pain or pressure pain. In addition, you can also draw blood to test whether there is an increase in creatine kinase, such as dystonia, Parkinson’s disease, there will also be double lower limb soreness; 4, lumbar disc herniation, lumbar spinal stenosis: will cause lower limb nerve compression, early will also cause thigh soreness, accompanied by limb activity disorders, with the development of the disease, clinical symptoms will worsen, can appear numbness, pain, activity restrictions, and even cause intermittent claudication; 5, lower limb vascular diseases: such as varicose veins and lower limb artery occlusion, can also lead to leg muscles, tissue metabolic disorders, can show thigh soreness and swelling, lower limb weakness.