Grade 3 cystic-solid nodules are breast nodules with both cystic and solid components, with a high likelihood of being benign and a <2% probability of being malignant. A cystic-solid breast nodule means that the nodule contains both cystic and solid components, and may be the manifestation of benign breast diseases such as cysts and intraductal papillomas containing solid components, or may be the imaging manifestation of malignant tumors such as breast cancer. The BI-RADS classification is a benign and malignant risk assessment of breast nodules based on breast ultrasound, mammogram and other imaging examinations. Grade 3 nodules are those with a high likelihood of being benign and a 0-2% likelihood of being malignant. A grade 3 cystic-solid nodule indicates a higher likelihood that the nodule is a cyst with a solid component, an intraductal papilloma, or other disease, but a <2% likelihood of breast cancer. In general, patients should be followed up regularly to observe whether the nodule has progressed, and if the patient is old and anxious, puncture biopsy may be considered to further clarify the benign or malignant nature. It is recommended that patients consult a specialist and make a comprehensive judgment by combining the other descriptions in the report and other imaging results.