There are different causes of bumps around buttocks during chemotherapy, such as folliculitis, allergic urticaria, eczema, etc. You can apply mupirocin ointment, chlorpheniramine maleate tablets, zinc oxide ointment and other medications according to the situation. 1. Folliculitis: During chemotherapy, it is easy to reduce the white blood cells and body resistance, which can induce bacterial or fungal infections leading to folliculitis around the buttocks, if it is caused by bacterial folliculitis, you can use mupirocin ointment for topical treatment, if it is caused by fungal infection, you can apply ketoconazole cream for topical treatment. 2. Allergic urticaria: During chemotherapy, goose bumps around the buttocks may also be caused by chemotherapy drugs allergic urticaria, which can be treated with chlorpheniramine maleate tablets, dexamethasone tablets and other anti-allergy drugs. 3. Eczema: Eczema can also appear during chemotherapy when the resistance is weak, resulting in bumps around the buttocks, sometimes accompanied by oozing, you can apply zinc oxide ointment, compound dexamethasone acetate cream and other topical treatment. There may be other reasons for the bumps around the buttocks during chemotherapy, and it is recommended that patients choose the appropriate treatment for themselves according to the cause under the guidance of the doctor.