Different causes of enlarged lymph nodes are eliminated in different ways, and common causes include lymphadenitis, connective tissue disease, malignant tumors and so on. The main treatments are medication and surgery. 1. Lymphadenitis: if the lymphadenitis is caused by bacteria, you need to take amoxicillin, cefaclor and other antibiotics; if it is caused by virus, you can take acyclovir, ribavirin; if it is tuberculosis lymphadenitis, you can take isoniazid, rifampicin, ethambutol and other drugs. 2. Connective tissue diseases: such as systemic lupus erythematosus, nodular disease, etc., may lead to related lymph node enlargement. Clinical treatment is based on drug therapy, using adrenal glucocorticosteroids (e.g., prednisone, prednisone, etc.), cytotoxic drugs (e.g., methotrexate, etc.) for anti-inflammatory and immunomodulatory purposes. 3. Malignant tumors: many kinds of malignant tumors can lead to enlargement of corresponding lymph nodes through lymphatic metastasis, while lymphoma, lymphoblastic leukemia can directly invade lymph nodes and lead to enlargement. Clinical oncologists are needed to conduct detailed examination, and after clear diagnosis and condition, combined with surgery, radiotherapy, chemotherapy, targeted therapy, bone marrow transplantation and other comprehensive treatment measures. If lymph node enlargement occurs, one should consult the doctor in time, complete the examination, make a clear diagnosis, and then follow the doctor’s instructions to give active treatment.