Coughing at night and in the morning is considered to be related to cardiac insufficiency, cough variant asthma, respiratory infections and other diseases, which need to be treated in different ways according to different causes. 1. Cardiac insufficiency: it can lead to pulmonary stasis, which in turn causes the patient to cough; lying down at night and moving around in the morning can lead to an increased burden on the heart and a strong cough. For the cough caused by cardiac insufficiency, treatment with cediran and digoxin to strengthen the heart; furosemide and spironolactone diuretic; nitroglycerin and sodium nitroprusside vasodilator and other drugs for treatment, and appropriate restriction of water intake. 2. Cough variant asthma: airway spasm is easy to occur at night and in the morning, which can lead to cough aggravation. It can be clearly diagnosed by lung function and bronchodilator test. Treatment can be done with drugs such as budesonide, montelukast sodium and salmeterol. 3. Respiratory infections: for example, in bronchitis and pneumonia, respiratory secretions increase, and when changing position at night and in the morning, the flow of sputum can stimulate the mucous membrane of the respiratory tract, which leads to a more severe cough. Give sensitive antibiotics such as cefotaxime and azithromycin after it is clear that there is a bacterial infection. Coughing at night and in the morning may also be associated with other diseases, which require prompt medical attention and medication as prescribed by the doctor after the cause of the cough is clarified, and cough suppressants should not be taken on their own to prevent masking and delaying the condition. The above drugs should be used under the supervision of a physician.