The two fever reducers should never be taken together. The two fever-reducing drugs include both oral two fever-reducing drugs and oral fever-reducing drugs plus topical fever-reducing drugs, both of which should not be used together. If two kinds of antipyretics are taken together, it will increase the possibility of deficiency on the one hand, and on the other hand, it will increase the adverse reactions of kidneys, liver damage and gastrointestinal tract. Therefore, the two antipyretics must not be taken together, and it is recommended to choose one of the antipyretics. Repeated fevers should be used once at intervals of 4-6 hours, but not more than four times in 24 hours. If fever is not relieved after three days of using antipyretic drugs, it is recommended to stop the medication early and seek the help of a doctor or pharmacist.