In clinical practice, clopidogrel can be used as a long-term alternative to aspirin, the specific use of the drug should be in accordance with the individual’s physical condition and the doctor’s instructions for the rational use of drugs. Clopidogrel and aspirin are clinically used to inhibit platelet aggregation, the clinical indications are basically the same, aspirin enteric-coated tablets are the most commonly used clinical antiplatelet drugs, can prevent the coronary artery unstable plaque rupture, so patients with coronary artery disease need to take this drug for life. Some patients are allergic to aspirin enteric-coated tablets, or take aspirin after repeated bleeding events such as bleeding gums, gastrointestinal bleeding, etc., at this time, you can use clopidogrel for alternative treatment, but some patients in the use of clopidogrel may also cause gastrointestinal tract damage, bleeding, etc., so you should be in the doctor’s instructions to use the drug reasonably, do not change the drug privately. Of course, aspirin also has an anti-inflammatory and analgesic effect, and this therapeutic effect of clopidogrel can not be replaced. It is recommended that if you need to change the drug, you should be under the guidance of the doctor, according to the specific condition of the drug, do not blindly take the drug to avoid accidents.