Herpes simplex is a more likely cause of blistering on the lips due to fire. The disease is caused by a decrease in local resistance, such as fire, fatigue, cold or diabetes, the patient’s blood sugar control and cause the body’s resistance to reduce, the virus to take advantage of the situation and infect the skin around the mouth, causing erythema and blistering. The main treatment is antiviral treatment, you can take oral acyclovir tablets and valacyclovir hydrochloride tablets, the general course of treatment is about 10 days. For specific diagnosis and treatment, it is recommended to give reasonable diagnosis and active treatment under the guidance of clinicians.