Topical use of Silver Sulfadiazine Cream to treat wounds may be damaging to liver function. Topical absorption of Silver Sulfadiazine Cream may result in systemic adverse reactions, which may include liver damage such as jaundice and hepatic decompensation. Localized transient pain may occur after topical absorption of Silver Sulfadiazine Cream, which may also lead to systemic adverse reactions, which contain liver damage such as jaundice and hepatic decompensation, or even lead to acute hepatic necrosis. In addition to the above, this product may also cause adverse reactions such as drug rash, joint pain, and fever. Silver sulfadiazine cream is an antimicrobial drug mainly used for the prevention and treatment of small mild burns complicated by wound infections. It is contraindicated for those who are allergic to this product. Elderly and weak, suffering from AIDS, hepatic and renal hypoplasia and other diseases, pregnant and lactating women should use this product with caution. If you need to take silver sulfadiazine cream locally, you should go to the hospital in time, actively cooperate with the doctor’s treatment plan, follow the doctor’s instructions, do not blindly take the drug on your own.