Ozone therapy for lumbar disc herniation requires only a 19-22 G puncture needle and is simple and non-invasive. Ozone is a very active chemical substance, which is quickly (half-life of 20 min) decomposed into O2 and O- after injected into the intervertebral disc and paravertebral space, and the residual O- can be combined with each other to form O2, so there is no worry about the long-term residual ozone causing harm. The advantages of ozone treatment for lumbar disc herniation are: 1, ozone is extremely unstable and easily decomposed into oxygen, which will not cause secondary pollution and lasting organ tissue damage; 2, ozone has strong ability to destroy the nucleus pulposus tissue, but has no significant adverse effect on the paravertebral tissue; 3, ozone is inexpensive and does not require high surgical monitoring equipment, which reduces the cost of surgery; 4, the operation is non-invasive, simple and less painful for patients; 5, ozone has a sterilizing effect and generally has a low level of surgical monitoring equipment. 5.Ozone has a sterilizing effect, and disposable puncture needles are generally used, which can greatly reduce the incidence of postoperative infection.