1, laryngeal complications: according to statistics, otorhinolaryngology patients with laryngeal symptoms and vocal disorders, about half of the gastroesophageal reflux as the cause of its pathogenesis, or for the development of the relevant factors. Laryngeal symptoms related to reflux include chronic vocal difficulties, intermittent vocal difficulties, vocal cord fatigue, broken voice, long-term throat-clearing habits, excessive laryngeal mucus, postnasal flow, chronic cough, dysphagia, hysterical ballooning, and so on. Reflux as the cause or synergistic factors are reflux laryngitis, subglottic stenosis, laryngeal cancer, vocal fold contact ulcer or granuloma, post vocal fold stenosis, unilateral or bilateral arytenoid cartilage fixation, paroxysmal laryngospasm, pharyngeal hysterical bulbous sign, vocal fold nodules, polypoid degeneration, laryngeal cartilage chondrosis, laryngeal chondrodystrophy, laryngeal thick dermatomycosis and laryngeal leukoplakia. 2, chronic cough gastroesophageal reflux is an important cause of chronic cough, ranking the third cause of the cough, from children to adults. Chronic cough is associated with both respiratory aspiration and neurologic reflexes. The afferent and efferent pathways of the nerve reflexes are via the vagus nerve. More than half of the coughs in GERD are dry, and 24-hour pH monitoring reveals that coughs are often seen during wakefulness and in the upright position rather than at night. Patients often do not have GERD symptoms such as heartburn and acid reflux, so 50% to 75% of patients deny a history of reflux. Prolonged pH monitoring was used to confirm that cough is often the only symptom, but there can be typical reflux symptoms, or atypical symptoms, such as chest pain, nausea, asthma and hoarseness. 3, asthma: asthma patients, the incidence of GERD has been reported in different investigations. Perrin-Foyolle et al. (1989) from 150 consecutive asthma patients found that 65% of patients with reflux symptoms. connell (1990) reported 189 consecutive cases of asthma, 72% of heartburn symptoms, half of the patients with heartburn at night when supine position. 18% had a burning sensation in the throat at night. field et al. (1996) reported that of 109 asthma patients, 77% had heartburn symptoms, 55% had regurgitation, 24% had dysphagia, and 37% required at least 1 antireflux medication. Another 527 adult asthmatics reported by 6 hospitals in 4 countries had gastroesophageal reflux confirmed by esophageal pH monitoring in 362 cases (69%). In 186 consecutive asthmatic patients observed endoscopically, 39% had esophageal mucosal erosion or ulcer formation, and 13% had Barrett’s esophagus. Esophageal hiatal hernia, an indirect manifestation of GERD, was present in 50% of asthmatics.Eight studies with a total of 783 asthmatic children were found to have GERD ranging from 47% to 64%, with a mean of 56%, which is approximately the same as the reported incidence in adults, as determined by a short pH test, prolonged pH monitoring, or radiographic visualization of the esophageal hiatal hernia (Sontag, 1999) . From the above material, it can be seen that gastroesophageal reflux and asthma often coexist, in children or adult asthma patients, the incidence of gastroesophageal reflux are very high, which deserves the attention and attention of clinicians. 4, oral complications: acidic stomach contents stay in the oral cavity can cause oral diseases, including dental erosion is the most prominent. Acidic material long-term role in the teeth, the formation of dental erosion, which is a long-term acid exposure chemical change process. At first, the surface of the enamel is eroded, the luster disappears; years of corrosion so that the enamel is gradually destroyed, the texture of the softer and acid-resistant dentin that is poorly exposed to the acid, under the action of the acid, the dentin destruction is more rapid. Allergy to temperature changes, sweets and acidic foods.Jarvinen (1988) studied 109 cases of people with upper gastrointestinal symptoms.55% of the patients with reflux esophagitis had oral symptoms such as burning sensation in the mouth, tongue sensitivity and painful ulcers. In another 117 patients with reflux, whose mouths, teeth and salivary glands were studied, the majority of patients frequently felt dry mouth, tooth sensitivity, nonspecific itching or burning sensations in the mouth, or pharyngeal symptoms (Meurman, 1994). In addition to gingivitis and periodontitis, patients with reflux may have enlarged salivary glands, particularly the parotid glands, as a result of chronic acid reflux. Enlargement of the parotid glands may be caused by repeated acidic reflux irritation of the mouth, which causes the parotid glands to overproduce.