Intercostal neuralgia needs to be diagnosed through clinical manifestations and examination, and it is recommended to go to the hospital as soon as possible for examination to clarify the cause of the disease and then targeted treatment. 1. Clinical manifestations: intercostal neuralgia is basically the same as the course of the intercostal nerves, with a semi-curved distribution from the thoracic back along the intercostal space down to the anterior midline. The range of pain is limited to the distribution area of the lesion intercostal nerve, mostly seen in the unilateral fifth to ninth rib. The pain is characterized by stabbing or burning pain, and the intercostal neuralgia can be induced by breathing movements, and the pain can be aggravated by coughing and sneezing, which makes the patient’s pain intolerable. There are pressure points on the skin along the distribution area of the intercostal nerve, and the most common pressure points are beside the spine, mid-axillary line, and beside the sternum. 2. Examination: Intercostal neuralgia should also go to the hospital to do chest CT examination, cardiac enzymes, electrocardiogram, etc., to exclude whether there are symptoms of myocardial ischemia and connective tissue lesions, to identify whether it is intercostal neuritis. When suspicious symptoms appear, it is recommended to go to the hospital in time and listen to the professional doctor’s opinion.