What are the treatment options for stomach cancer? Are there any new advances in the treatment of stomach cancer in recent years? First of all, the diagnosis should be clear and the stage and typing of the tumor should be analyzed through pathological diagnosis, on the basis of which the corresponding treatment plan can be given. For example, more than 90% of early gastric cancer patients can be removed through surgery; while progressive upper gastric cancer requires complete resection of gastric tissues and auxiliary pre-operative and post-operative radiotherapy. There is no major breakthrough in the treatment of gastric cancer in recent years, but there are more new advances and the treatment effect has been steadily improved. The new advances include the following aspects: firstly, the operation method is more standardized; secondly, the emergence of new drugs and auxiliary therapies has improved the treatment effect of gastric cancer; and most importantly, the concept of gastric cancer treatment has changed. In the past, the usual practice was that patients underwent surgery and postoperative adjuvant radiotherapy, but nowadays, through domestic and international clinical researches, the concept of perioperative adjuvant therapy is becoming more and more important, which means that adjuvant therapy is carried out before and after surgical treatment. This treatment can improve the survival rate of patients compared with the traditional surgical method. What are the means of preoperative adjuvant treatment? Preoperative treatment of gastric cancer has two main aspects, including preoperative radiotherapy and chemotherapy. Preoperative radiotherapy combined with chemotherapy is collectively called preoperative radiotherapy and chemotherapy, especially for upper gastric cancer, preoperative radiotherapy and chemotherapy can further increase the intraoperative lymph node clearance rate to 10-14%, and it seems that preoperative radiotherapy and chemotherapy for patients with stage II or III upper gastric cancer can further increase the 5-year survival rate of the patients when compared with preoperative chemotherapy alone. Is there any relevant research evidence to support this treatment? A clinical study usually needs to go through phase II and phase III clinical studies from research and development to application in clinical practice, which is relatively long in terms of time and takes at least 6 to 8 years before the final study results are available. The European CROSS study has demonstrated that preoperative radiotherapy can improve the rate of surgical resection of cancer as well as patient survival.