Dry syndrome combined with interstitial pneumonia, when pulmonary fibrosis occurs, the prognosis is worse, is more serious, can be life-threatening. Dry syndrome is a diffuse connective tissue disease, pathological changes for the gland mass lymphocyte infiltration, gland duct expansion, narrowing, etc., involving the respiratory tract, skin, lacrimal gland, etc. caused by dry mouth syndrome, interstitial pneumonia, pulmonary fibrosis. And the disease is progressive, there is no cure, mainly prevention-oriented, prevention and treatment of systemic damage, once interstitial pneumonia, is more serious, can aggravate the lung tissue damage, the prognosis is more bad. People with dry syndrome should pay attention to rest in daily life, quit smoking and alcohol, avoid cold, and follow the doctor’s instructions in a timely and reasonable standardized treatment.