The nine-valent vaccine is age-restricted and is recommended to be given between the ages of 16 and 26. The nine-valent vaccine can clinically prevent infection with nine HPV subtypes and can prevent 92% of cervical cancers, as well as vaginal cancers, vaginal epithelial lesions, cervical epithelial lesions and vulvar cancers. Therefore, vaccination with the nine-valent vaccine is very necessary. However, there are certain groups of people who should not be vaccinated, such as patients who are allergic to proteins, and women who are breastfeeding or pregnant. In addition, it is best to avoid menstruation when receiving the nine-valent vaccine.