Clinical symptoms of systemic lupus erythematosus include facial erythema pteroides, joint pain, fever, muscle pain, fatigue, mucosal ulcers and hair loss. Systemic lupus erythematosus is an autoimmune inflammatory connective tissue disease that can invade multiple organs. The clinical manifestations of SLE patients are quite diverse, and the early symptoms are often atypical, with common symptoms including pteroid erythema on the face, joint pains, fever, muscle pains, fatigue, mucosal ulcers and hair loss. As the condition of SLE progresses, it may gradually involve multiple organs and cause corresponding symptoms, such as generalized edema, hypertension, foamy urine in patients with lupus nephritis, shortness of breath and chest pain in patients with pericarditis. SLE patients can go to the rheumatology and immunology department of regular hospitals for detailed consultation and standardized treatment according to the doctor’s instructions.