The manifestations of cholangiocarcinoma after puncture and drainage mainly include abdominal pain, fever, electrolyte disorder, bleeding and so on. 1. Abdominal pain: after puncture and drainage of cholangiocarcinoma, the wound will be bandaged, and the pain will appear if the bandaging is not standardized or the local tissues are pressed. 2. Fever: after puncture and drainage of cholangiocarcinoma, the drainage tube will cause wound infection, and fever will appear after continuous infection. 3. Electrolyte disorder: after puncture and drainage of cholangiocarcinoma, the bile will be drained to the outside of the body, resulting in loss of body fluid and electrolyte disorder. 4. Bleeding: after surgery, a drainage tube is left in the body, which rubs the surrounding tissues and easily causes the surrounding tissues to break in the long run, thus bleeding occurs. After puncture and drainage of cholangiocarcinoma, pay attention to fixing the drainage tube to prevent it from falling off, meanwhile keep the mouth of drainage tube and the surrounding wounds clean and dry to avoid infection, pay attention to observing the nature, color and flow of liquid drained from the bile ducts, and go to the hospital in time to consult the physician’s guidance in case of any uncomfortable symptoms.