It is possible for weakly positive antinuclear antibodies to become negative.
Antinuclear antibody is one of the commonly used laboratory tests in rheumatology and immunology department. Antinuclear antibody is an important marker for autoimmune diseases and is the first choice of screening test for SLE, but weak positive antinuclear antibody can also be seen in healthy people, especially the elderly, in addition, patients with viral hepatitis, lung cancer, hepatocellular carcinoma and other diseases can also have weak positive antinuclear antibody.
Patients with weakly positive antinuclear antibodies caused by autoimmune diseases such as systemic lupus erythematosus, desiccation syndrome and viral hepatitis may turn negative after standardized and timely treatment, while healthy people with weakly positive antinuclear antibodies are regularly observed in the hospital.
Laboratory test results need to be interpreted by a professional physician, it is recommended that patients go to the Department of Rheumatology and Immunology of a regular hospital to further clarify the causes of weakly positive antinuclear antibodies, and follow the doctor’s instructions for treatment.