Cholesterol-lowering drugs are recommended to be taken at night about one hour before going to bed, because the flow efficiency of the human blood system slows down during the sleep phase, which can easily lead to the formation of cholesterol substances in the inner walls of blood vessels and increase the possibility of vascular embolism in patients. Taking cholesterol-lowering drugs before sleep can speed up the efficiency of cholesterol decomposition and metabolism in the body and reduce the concentration of total cholesterol in the blood by increasing the speed of secretion of rate-limiting enzymes by the active cells of the liver of the patient. For patients with high total cholesterol, in addition to receiving standardized medication, good diet and life care measures have a positive impact on maintaining the stability of the disease, including a light diet, a balanced diet structure, and moderate physical exercise.