Skin melanin deposits can be relieved with topical creams containing hydroquinone cream, arbutin, niacinamide and other ingredients. 1. Hydroquinone cream: a kind of medicine for skin diseases, mainly used to treat chloasma, freckles, acne, trauma-induced hyperpigmentation and dark changes. There is irritation, it is recommended to use at night, wash the skin and rub it on the area with spots. If you find a difference, you need to stop using it. 2. Arbutin: Arbutin is safer, so it works well even for people with sensitive skin. Because it does not make the skin more sensitive to the sun. 3. Niacinamide: Niacinamide works on the skin to inhibit the production of melanin and effectively inhibits the transmission of melanin to the cells of the stratum corneum. Niacinamide is irritating to the skin and needs to be discontinued if severe intolerance occurs. Skin melanin precipitation may also have other treatments, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to develop a scientific treatment program, do not self-medication, so as not to cause adverse effects.