Sputum culture is generally more accurate than blood tests for mycoplasma detection, but the detection rate is lower. Culture of sputum specimen to isolate mycoplasma is decisive for the diagnosis of mycoplasma infection, the accuracy is significantly higher than other tests, but the detection rate is lower and the time taken is longer. Blood sampling and checking blood routine has certain value for the diagnosis of mycoplasma infection, and it can be seen that the white blood cells are normal or slightly increased, with neutrophils increased mainly, with lower specificity; it can also be done to check the serum mycoplasma antibody by the condensate collection test, and it has more diagnostic value if it is positive and the titer is gradually increased. At present, mycoplasma infection diagnosis is also commonly used in the throat swab check mycoplasma antigen, with early diagnostic value. Mycoplasma infections need to do the diagnosis of the examination is recommended to consult a professional physician, often need to synthesize the clinical symptoms, X-ray imaging performance and serological examination results to determine.