PAX8 positive means that there is oncogene positive, may be the occurrence of kidney tumors, thyroid tumors, or thymus tumors, etc., need to do further examination to clarify the cause of the disease, and timely treatment.
PAX8 is a specific marker for kidney tumors, thyroid tumors, and thymus tumors, etc. PAX8 positivity often means that such cancers may have occurred, and can be used in the diagnosis and differential diagnosis of cancer. However, even if a cancer gene is detected, there is only a little reference significance, and the chances of possible cancer are a little higher.
Therefore, only through this one test can not be completely clear, patients need to use a combination of multiple immunohistochemical markers as well as imaging tests in order to make a correct diagnosis.
Kidney tumors need to be surgically removed in the early stage, and in the late stage, drugs such as sunitinib malate capsules can be applied for targeted therapy. Patients with thyroid tumors need to be treated with surgical resection, and some patients need to be treated with iodine-131 radiation therapy after surgery. Thymus tumor is mainly treated by surgery, if it cannot be completely removed, radiotherapy can be added after surgery, and cisplatin and paclitaxel can be used for chemotherapy.
The above treatments and medications should be taken under the guidance of a doctor.
If pax8 is positive, it is recommended to go to regular hospital for clear diagnosis and standardized treatment.