The infraorbital foramen is located approximately 0.5 cm below the midpoint of the inferior orbital rim and is an oval shaped hole. The infraorbital nerve and blood vessels pass through the infraorbital foramen, and the infraorbital foramen leads posteriorly superiorly and laterally into the infraorbital canal. The infraorbital foramen is the entry site for infraorbital nerve block anesthesia. Infraorbital nerve block anesthesia through the infraorbital foramen can inject anesthetic into the infraorbital canal to anesthetize the nerves in the upper alveolar socket, and it can be used for extractions of maxillary incisors and premolars, or revision of the alveolar process, as well as anesthesia for cysticercosis, cleft lip and other surgeries. The infraorbital foramen can also be used to anesthetize surgical procedures in otorhinolaryngology. Trauma to the maxillofacial area that injures the maxilla or maxillary sinus may also cause injury to the infraorbital nerve in the infraorbital foramen, resulting in numbness of the maxillofacial area.