Whether the sequelae of TIPS surgery can be favored or not needs to be decided by the severity of symptoms and whether the disposition measures are timely when. TIPS refers to Transjugular Intrahepatic Portal Vein Stent Shunt (TIPS), which is an interventional therapy for the treatment of upper gastrointestinal hemorrhage due to portal hypertension, utilizing the principle of surgical shunt to establish an artificial shunt channel between the hepatic vein and portal vein within the hepatic parenchyma, so as to lower the portal pressure, and to reduce or eliminate ruptured bleeding of varices in the esophagus and ascites and other symptoms caused by portal hypertension. Sequelae such as hepatic encephalopathy are more difficult to treat and are relieved by medication; sequelae such as abdominal hemorrhage, pericardial tamponade, biliary injury, postoperative infection, and so on can be treated well by surgery and medication if the symptoms are mild; if the symptoms are serious, it is more difficult to treat them and it is more difficult to treat them well. In order to minimize the sequelae of TIPS surgery, we should do a good job of evaluating the patient’s condition and surgical risk before surgery, pay attention to postoperative observation, and treat the complications as soon as possible, which can improve the success rate of the treatment of sequelae and complications.