Craniosynostosis is not an uncommon disorder and there are a large number of patients with craniosynostosis in our country. Craniosynostosis is often a very unexpected occurrence and therefore has no specific tendency. Craniosynostosis can occur in people of all ages, including children. So what are the effects of cranial defects in children? Cranial defects in children can have a significant impact on the affected child. Firstly, due to skull loss, the relative balance of pressure inside and outside the skull and pressure in the physiological space of the skull is broken, which will affect the normal development of the skull and brain and may increase the chance of epilepsy; secondly, due to the lack of protection of the hard shell of the skull, the risk of brain tissue damage increases; in addition, children with skull loss often have timidity and even low self-esteem, parents should consider the aesthetic problems of children and have skull loss performed as early as possible. In addition, children with cranial defects are often timid and even have low self-esteem. Children should pay more attention to the choice of repair materials for cranial repair. Currently, polyether ether ketone, or PEEK, is commonly used for cranial repair in developed countries. In China, this material complies with the national industry standard YY/T0660-2008 for surgical implants, and its excellent performance, better histocompatibility, elasticity, thermal insulation, lightness, and stability, which are basically equivalent to human cranial bone, are very suitable for pediatric patients.