Normal liver function with liver palms may be caused by physiological factors, but also may be caused by liver disease, rheumatoid arthritis and other diseases, the former cause no special treatment, the latter cause need to be under the guidance of the doctor for targeted treatment, such as general treatment, drug treatment and so on. 1. Physiological factors: hormone level changes in pregnancy and puberty can also cause liver palms; in addition, the redness of the palms may not be liver palms; the above cases are normal physiological phenomena and do not require special treatment. 2. Liver disease: when liver disease causes liver fibrosis and does not enter the decompensated stage, it can also be manifested as normal liver function but with liver palms, which should be treated positively; for example, viral hepatitis needs to be treated with antiviral drugs such as entecavir and fatty liver disease should be avoided by avoiding drinking alcohol and eating high-fat food, and with dyslipidemia, it can be treated by taking drugs such as fenofibrate. 3. Rheumatoid arthritis: it can affect the secretion of estrogen and lead to liver palms, and ibuprofen can be used to relieve the pain during the acute active period, and methotrexate can be used to relieve or control the condition. Liver function is normal with liver palms after exclusion of physiological factors, it is recommended to go to the hospital, please doctor’s judgment, give treatment plan.