For information on the following treatment options, see the Treatment Options Overview section
Stage 0, A, and B adult primary liver cancer
Treatment of stage 0, A, and B adult primary liver cancer includes the following approaches:
Monitoring of lesions smaller than 1 cm.
Partial hepatectomy.
Total hepatectomy and liver transplantation.
Tumor ablation may be performed using one of the following methods:
Radiofrequency ablation.
Microwave ablation.
Transdermal alcohol injection.
Cryoablation.
Clinical trials of electroporation therapy.
Use the Clinical Trial Search tool to find NCI clinical trials that are enrolling patients.Searches can also be done by cancer type, patient age, and trial site. General information about clinical trials is available.
Stage C, and D Adult Primary Liver Cancer
Treatment of stage C and D adult primary liver cancer includes the following approaches:
Embolytic therapy using one of the following approaches:
hepatic artery embolization (TAE).
Hepatic artery chemoembolization (TACE).
Tyrosine kinase inhibitor targeted therapy.
Immunotherapy.
Radiotherapy.
Clinical trials of targeted therapies after chemoembolization or chemotherapy combined with targeted therapies.
Clinical trials of new targeted therapeutics.
Clinical trials of immunotherapies.
Clinical trials of immunotherapy combined with targeted therapies.
Clinical trials of stereotactic radiotherapy or proton beam radiotherapy.
Use the Clinical Trial Search tool to find NCI clinical trials that are enrolling patients.Searches can also be performed by cancer type, patient age, and trial site. General information about clinical trials is available.