Why does breast cancer luminal A metastasize?

Breast cancer luminal A appears to metastasize, which may be related to the tumor cells entering into the blood vessels and lymphatic vessels and transferring to the patient’s other organs with the blood and lymphatic circulation, forming breast cancer metastases. In patients diagnosed with breast cancer, a portion of the tumor tissue is usually taken for typing. Patients who are positive for both estrogen and progesterone receptors, have a proliferation index Ki-67 of less than 14%, and are HER-2 negative are classified as Luminal A breast cancer. The treatment of Luminal A breast cancer that has developed distant metastasis is mainly systemic adjuvant therapy, which mainly includes chemotherapy, endocrine therapy and radiotherapy. Some patients with Luminal A type middle and advanced breast cancer can achieve the effect of downstaging after systemic adjuvant therapy, and get the opportunity of surgery, through which they are expected to achieve clinical cure. Luminal A breast cancer patients are recommended to follow the doctor’s instructions for standardized treatment, so as to avoid delaying the disease.