There is no definite value for the cure rate of cirrhosis at 20 years of decompensation, and it needs to be judged in the context of the severity of the disease. If the condition is stable, then there is a possibility of cure, but if there is a deterioration of the condition, then even after surgical treatment, the possibility of cure is relatively low. The uncompensated phase of cirrhosis refers to the various complications of portal hypertension that occur during the course of the disease, such as ascites, rupture and bleeding of esophagogastric varices, sepsis, and hepatorenal syndrome, etc. Ascites is one of the more common forms of cirrhosis. Ascites is one of the more common symptoms, due to the different patients, the specific degree of the disease varies, so cirrhosis loss of compensation 20 years of cure rate is very difficult to judge. If the patient’s condition has been relatively stable, then there is still a chance of cure, the patient can take some antiviral drugs under the guidance of the doctor, such as entecavir dispersible tablets and adefovir capsules, etc., so as to improve the condition. However, if the patient’s condition worsens, the possibility of cure is lower, and the patient can control the development of the disease through liver transplantation to prolong life. During the treatment period, patients should strictly follow the doctor’s arrangement, develop healthy living and dietary habits, take more rest, and keep an optimistic and cheerful mindset, do not put too much pressure on themselves, so as not to aggravate the condition.