Patients with stage 1c endometrial cancer with low differentiation can be treated by surgery, radiotherapy and chemotherapy. 1. Surgery: the main treatment method after diagnosis of endometrial cancer is surgical resection, and radical surgical resection is often feasible for stage 1c patients, after which radiotherapy and chemotherapy can be supplemented according to their conditions. 2. Radiotherapy: it is one of the effective therapies for treating endometrial cancer, often combined with chemotherapy. 3. Chemotherapy: it is a systemic therapy to make chemotherapy drugs reach the lesions through venous blood, postoperative chemotherapy can effectively reduce the recurrence rate of low-differentiated endometrial cancer patients after operation and reduce distant metastasis outside the pelvis. Patients need to actively cooperate with doctors for treatment after diagnosis.