The sudden appearance of small white spots on the skin is considered to be vitiligo, florid furuncle, simple furuncle, etc. The main treatments include medication, physical therapy and so on. 1. Vitiligo: vitiligo is related to the destruction of melanocytes, the main symptom is the appearance of white spots, you can apply glucocorticoid drugs, such as mometasone furoate, trimethoprim and so on, for the face and mucous membranes and other delicate parts, you can apply tacrolimus ointment, pimecrolimus cream, but also need to cooperate with the phototherapy and other physical methods of comprehensive treatment. 2. florid chafing: florid chafing is mainly caused by malassezia invasion of the skin, there may be white lesions, mainly apply antifungal drugs, such as naftifine, ketoconazole, etc., you can also apply sulfur dioxide lotion, benzoyl peroxide and other drugs. 3. Furfury simplex: Furfury simplex is common in children and adolescents, mainly white spots on the face, this disease is self-limiting, generally do not need treatment, you can use some urea ointment, vitamin E cream and other moisturizing. Suddenly appear small white spots on the skin, to go to the hospital for a detailed examination to clarify the cause of standardized treatment, the above drugs should be used in accordance with medical advice.