Sacroiliac arthritis is an inflammatory disease caused by trauma, strain, autoimmune diseases and other factors. Commonly used treatment drugs include anti-inflammatory and analgesic drugs such as ibuprofen and anti-rheumatic drugs such as methotrexate, and there is no special drug that can only be used for treating this kind of disease. 1. Anti-inflammatory and pain-relieving drugs: Ibuprofen, diclofenac sodium and so on. Ibuprofen can relieve mild, moderate pain may be nausea, stomach pain, vomiting and other adverse reactions; gastrointestinal bleeding or perforation of the patient is prohibited. Diclofenac sodium has obvious analgesic, anti-inflammatory and antipyretic effects, may produce chest tightness, nausea, diarrhea and other adverse reactions; lactating women and children are prohibited. 2. Anti-rheumatic: If the patient’s sacroiliac arthritis is caused by ankylosing spondylitis, anti-rheumatic drugs such as methotrexate can be taken, methotrexate can effectively relieve rheumatic patients with disease symptoms and slow down the progress of joint damage. It may produce headache, nausea, fever and other adverse reactions; liver and kidney dysfunction is prohibited. 3. Closed injection: If the patient has severe pain, local injection of closed drugs such as Triamcinolone acetonide can be used to relieve the pain. Triamcinolone acetonide has significant anti-inflammatory and analgesic effects, and may produce headache, chest tightness and other adverse reactions; infectious skin disease is prohibited. Patients should take the medication with the use of heat, microwave, acupuncture and other modalities of physical therapy. All medications should be taken under the guidance of a physician, and patients should go to the hospital in a timely manner.