High total bilirubin of 200μmol/L with jaundice may be caused by physiological factors or diseases such as cirrhosis, hepatitis, gallstones, etc. Physiological factors are not serious, while diseases are more serious, but the prognosis of some of these diseases is not bad after active treatment. High total bilirubin with jaundice may be caused by physiological factors, commonly seen in neonatal jaundice, which may subside within a week after birth and is not serious. High total bilirubin with jaundice can also be caused by hepatitis, cirrhosis and gallstones, which are more serious. However, gallstones can be cured with standardized treatment, and hepatitis patients can be stabilized with standardized medication and the prognosis is not bad. If you have high total bilirubin with jaundice, it is recommended to go to the hospital after eliminating physiological factors.