Differences between China’s New Crown vaccine and Pfizer’s vaccine include the technical route and dosage form. The main difference is the technical route. Chinese neocoronavirus vaccines include the inactivated vaccine of Beijing Kexing, the recombinant protein vaccine of Anhui Zhifei, and the adenovirus vector vaccine produced by Kangxinuo, which are made through the technology of inactivating neocoronavirus, recombinant protein, and adenovirus as a vector, respectively, whereas Pfizer vaccines belong to the category of mRNA vaccines, which implant coded specific antigens into the vaccine. Secondly, there is a difference in the dosage form, Pfizer’s vaccine requires four injections, while our inactivated vaccine and recombinant protein vaccine require two and three injections respectively, and the adenovirus carrier vaccine is a one-shot dose, and the inactivated vaccine and adenovirus carrier vaccine currently require booster injections after the full six months of vaccination.