There is no such thing as the most effective way to cure stomach cancer, but we need to adopt suitable treatment modes according to the condition of the disease, including surgery, radiotherapy, targeted therapy, etc. The treatment options of stomach cancer are related to the pathological stage, location and tissue type. Gastric cancer is a malignant tumor originated from gastric mucous membrane epithelium, and its treatment plan is related to the pathological stage, location and tissue type of gastric cancer, etc. Surgery, radiotherapy and targeted therapy can be chosen. Surgery is divided into radical surgery and palliative surgery. Chemotherapy is used for preoperative, intraoperative and postoperative of radical surgery, especially for those after radical surgery for progressive gastric cancer, after palliative surgery, and recurrence after radical surgery. Targeted therapy can target damage to cancer cells and reduce normal cell damage. Therefore, gastric cancer patients need to combine with their own disease development, follow the doctor’s instruction to adopt suitable treatment and avoid unauthorized use of drugs.