There are side effects of using too much cork, which can lead to diarrhea, reduce the sensitivity of the drug, and dependence on the drug, as follows: 1. If the long-term use of the intestinal wall will be repeatedly stimulated, and even cause mucosal damage, reducing the sensitivity to drugs. 3, dependence, drugs can only play a certain auxiliary role, the treatment of constipation needs to be based on dietary regimen, to develop good eating habits and habits of life. Long-term use of open cork will make the body to drug dependence, the formation of stubborn constipation, but will aggravate the patient’s condition.