The most obvious difference between ulcerative colitis and intestinal cancer is the nature of the disease, the former is an inflammatory disease, the latter is a tumor disease, and there are also differences in symptoms and treatment. 1. Ulcerative colitis is a chronic non-specific inflammatory disease; bowel cancer usually refers to colorectal cancer, which is a malignant tumor of digestive tract. These two diseases are different in nature, but ulcerative colitis has the possibility of developing into colorectal cancer. 2. Symptoms of ulcerative colitis mainly include recurrent diarrhea, abdominal pain, mucus, pus and blood stools, etc. The condition is chronic, with alternating episodes and remission. Early stage of colorectal cancer has no obvious symptoms, but gradually there may be changes in defecation habit, changes in fecal character, emaciation, abdominal mass and so on. 3. The treatment of ulcerative colitis is mainly based on medication, and aminosalicylic acid preparation such as mesalazine and olanzapine is often used in mild and moderate degrees, and glucocorticoid such as prednisone and methylprednisolone is often used in moderate and severe degrees. Early stage of colorectal cancer is mainly treated by surgery, which can achieve radical cure. In middle and late stages, comprehensive treatment is mostly adopted, and surgical treatment is supplemented by radiotherapy and targeted therapy. The above is part of the difference between ulcerative colitis and colorectal cancer, the specific differential diagnosis needs to be carried out by professional doctors, and the use of drugs needs to follow the doctor’s prescription.