Having thyroid nodules at the age of 13 is usually abnormal and may be related to thyroiditis, goiter, thyroid cancer and other diseases. 1. Thyroiditis: mainly divided into infectious and non-infectious, infectious thyroiditis is usually associated with infection with bacteria and viruses, while non-infectious thyroiditis is associated with autoimmune factors. The disease is an abnormal manifestation, need to be targeted as soon as possible to avoid repeated stimulation of the inflammation of the thyroid gland, resulting in the enlargement of the nodule. 2. Goiter: abnormal proliferation of thyroid follicular epithelial cells is also an abnormal manifestation, and the disease has a certain heredity. Once diagnosed, it should be treated as soon as possible, and if necessary, it can be treated with antithyroid hormone drugs, such as propylthiouracil and methimazole, as prescribed by the doctor. 3. Thyroid cancer: it is a malignant tumor of the thyroid gland, mainly originated from the follicular epithelium of the thyroid gland, manifested as painless neck nodules or hard lumps, which is an abnormal manifestation and needs targeted treatment. Once the diagnosis is confirmed, it is recommended to do lobectomy as soon as possible, as well as with isthmus lobectomy, followed by lymph node dissection. If only a nodule is found in the thyroid gland, it should be consulted as soon as possible and preliminary diagnosis should be made through physical screening and routine laboratory tests; in order to exclude malignant tumors, X-ray examination of the neck, CT examination, and biopsy and histopathological examination should be done as soon as possible.