Hair in the middle of a bald piece may be due to baldness, ringworm, congenital baldness and other factors, need to clarify the cause of the disease, symptomatic treatment, common treatment drugs are minoxidil, itraconazole, etc., if necessary, can also be physical therapy. 1. Patch baldness: commonly known as “ghost shaving”, may be associated with emotional stress, endocrine factors, autoimmune factors, etc., is a sudden patchy alopecia, alopecia areata border is clear, no scarring, no inflammatory reaction. Local use of dexamethasone, minoxidil, anthralin and other drugs; ultraviolet irradiation, photodynamic therapy and other physical therapy have a certain therapeutic effect on baldness. 2. Tinea capitis: it is an infectious disease caused by dermatophytes infecting the scalp and hair, which may manifest as hair loss, scaling, itching and other symptoms, and permanent baldness may occur when the condition is serious. Itraconazole, terbinafine, fluconazole and other drugs can be taken orally, but also assisted by clotrimazole, miconazole and other local drug therapy. 3. Congenital baldness: most of them are related to epidermal dysplasia, epidermal nevus, non-scarring limiting baldness and other diseases, which can be manifested as baldness on the top, and the hair is mostly lost within 1~6 months after birth, and there is no more hair growth, which may be accompanied by congenital developmental defects of nails, teeth, bones and other parts of the body. There is no effective treatment for this disease. A bald patch in the middle of the hair may also be caused by other factors, it is recommended that patients seek medical attention in a timely manner, and actively carry out relevant examinations to clarify the diagnosis, standardize the treatment under the guidance of the doctor, and avoid using medication privately, so as not to delay the condition.