Ultrasound may not always be able to detect endometrial cancer in women because some endometrial cancer patients will only have thickening of the endometrium but will not have the phenomenon of obvious lumps, which cannot be determined by choosing ultrasound at this time. Endometrial cancer is a kind of epithelial malignant tumor that occurs in the endometrium, and adenocarcinoma originated from endometrial glands is more common. Endometrial cancer is one of the three major malignant tumors of the female reproductive tract, accounting for 7% of systemic malignant tumors and 20%-30% of malignant tumors of the female reproductive tract. The most common symptom of endometrial cancer is irregular vaginal bleeding, especially in some older women. When irregular vaginal bleeding occurs after menopause, the size of the uterus and the thickness of the endometrium can only be detected by ultrasound, and the diagnosis can be made by endometrial curettage combined with postoperative pathology. Endometrial pathology is the gold standard for diagnosing endometrial cancer. Therefore, when patients have the above symptoms, they should consult the doctor in time, clarify the cause of the disease under the guidance of professional doctors and choose targeted treatment.