Acute thrombocytopenic purpura in children is a common disease in hematology, because of its sudden onset, skin bleeding spots, petechiae, nasal bleeding, gum bleeding and other bleeding manifestations are prominent, parents panic, anxious, to the hospital to ask doctors to find ways to alleviate the child’s condition as soon as possible. In the face of parents eagerly seeking treatment for their children, Western doctors put high doses of glucocorticoids, high doses of gammaglobulin, cyclosporine A, and even vincristine and cyclophosphamide on the patients, and even give broad-spectrum antibiotic treatment to try to stabilize and relieve the condition as soon as possible. As a routine treatment, this is something that all patients have experienced. The desperate wishes and feelings of the child’s parents are understandable, and the initial intentions of some doctors are also good. However, any kind of disease has its own rules, and acute thrombocytopenic purpura is no exception. Some biological factors (such as viral infection, bacterial infection, etc.), chemical factors (such as certain drugs, benzene), etc. act on the body, leading to the body’s immune function disorder, producing anti-self platelet antibodies or other mechanisms to destroy platelets, so that platelets are quickly destroyed, the blood circulation of platelets decreased, the normal hemostatic function is damaged, easy to bleeding, bleeding is not easy to stop. The organism faces the blow of some external factors and a momentary immune dysfunction occurs as a result of the organism’s stress response. The observation of a large number of cases shows that when children with acute thrombocytopenic purpura are first treated with appropriate symptomatic treatment and closely observed, after 4 to 12 weeks, the body itself or with appropriate intervention of drugs, after a certain period of time, can return to normal from the stress state, and most of those with acute onset can heal themselves. If the disease is not controlled at this stage and the course of the disease is prolonged, the acute cases will gradually develop into chronic thrombocytopenic purpura. The conventional treatment for immune thrombocytopenic purpura, western medicine uses high dose glucocorticoids, high dose gammaglobulin infusion, which can reduce platelet destruction and rapidly elevate platelets, but it does not mean that the body’s immune function has been restored to normal, but only the result of the body’s entire immune system is suppressed, cyclosporine A, vincristine, cyclophosphamide and other immunosuppressants are also roughly the same effect. The therapeutic effect of exogenous platelet transfusion, on the other hand, ends after the platelet survival period has expired. Therefore, the immune thrombocytopenic purpura in the acute phase or chronic phase of the acute onset of the pharmacological effect of the drug disappeared, the body’s immune function did not return to normal, still will destroy their own platelets, platelets will also come down again. Glucocorticoids, high-dose aprotinin, cyclosporine A, vincristine, cyclophosphamide and other immunosuppressants, or inhibit B lymphocytes, or inhibit reticuloendothelial cell function, or inhibit T-cell function, large doses and long courses of application in children whose immune system and other organ functions are not yet mature, the long-term effects are difficult to predict, and with the increase in the course and dosage, the The long-term effects are unpredictable, and as the course of treatment and dosage increase, so do the toxic side effects of the drug. The human immune system is very complex, the relationship between cellular and humoral immunity, the relationship between immune cell subgroups, how the body regulates various immune functions and the balance between immune cell subgroups are not very clear, not to mention that the immune system of children is not fully developed, and the immune function is still in the perfect stage. Obviously, it is not appropriate to give strong or long-term immunosuppressive treatment to primary thrombocytopenic purpura, which can suppress the abnormal immunity, but the suppression of normal immunity should not be ignored. It is difficult to imagine that the organism will coordinate the relationship between cellular and humoral immunity and immune cell subpopulations under immunosuppression and reach a normal balance. High dose or long course of immunosuppressive treatment for acute thrombocytopenic purpura in children should be cautious and immune thrombocytopenia should not be overtreated when systemic symptoms are not typical. In recent years, clinical observations have revealed that the number of children with acute thrombocytopenic purpura turning into chronic has increased, and it is difficult to say that the reasons for the change from acute to chronic thrombocytopenic purpura are not related to the initial overtreatment. Therefore, for chronic thrombocytopenic purpura, if you don’t adjust the treatment plan and strategy, and actively seek the treatment plan of traditional Chinese medicine, Chinese and western medicine, you are still in the vicious circle of treatment by simply using glucocorticoid, gammaglobulin, and platelet transfusion, you may always live in the pain of thrombocytopenia, bleeding, and huge side effects of western medicine.