Small intestinal mesenchymal tumor bleeding can be treated by surgical treatment and targeted therapy. 1. Surgery: Bleeding from small intestinal mesenchymal tumor may be caused by larger size or spread and metastasis. Surgery can be chosen to remove the tumor and achieve the effect of stopping bleeding. 2. Targeted therapy: if the bleeding range of the patient is relatively large, in the case of inability to perform surgical resection, you can consider following the doctor’s instructions to use targeted drug therapy, such as imatinib, sunitinib malate capsule, etc., which can play a therapeutic effect of stopping the bleeding and avoiding the production of some irreversible complications. It is recommended that patients with bleeding small intestinal mesenchymal tumors should go to regular hospitals in time to receive consultation and treatment, and take appropriate therapeutic measures under the guidance of professional doctors.