1, slow, insidious onset: more months or years to show some not obvious but different from the previous performance, or appear obvious abnormal speech, thinking ideas, behavior, etc.. The prognosis is generally poor. 2. Small age of onset: the younger the age of onset, the worse the prognosis, such as childhood illness, the prognosis is generally not good, and may be related to abnormal brain development. 3, the longer the disease: the worse the prognosis, the longer the duration of each attack, the treatment can not be alleviated, or although alleviated, but some symptoms remain, the more likely to relapse. 4, pre-morbid bad personality: pre-morbid withdrawn personality, sensitive and suspicious, thinking bizarre, absurd, etc., is a factor of poor prognosis. 5.Positive family history: The more people with psychosis in the family, the greater the number of patients with the disease, the worse the prognosis compared to those without a family history of psychosis. 6, symptoms are mainly negative symptoms: such as little speech, withdrawn, ignoring people, lazy, no desire, etc., without hallucinations, delusions, impulsive aggression and other positive symptoms, the prognosis is poor. 7, lack of family and social supporters: no family members and other care, supervision of medication, no one to help in case of trouble, etc., the prognosis is poor. 8.The prognosis is poor if the treatment is not timely and systematic, if the medication compliance is poor, and if the medication is frequently stopped, resulting in multiple relapses. 9.People with poor learning, occupational function and social relationship before the disease have poor prognosis. 10.People with abnormal brain structure have poor prognosis.