Patients often have “tumor psychology” such as doubt, anxiety, fear and depression, which have different treatment techniques. Doubt: It is mostly found in middle-aged patients who have strong desire to live, and it generally shows that they doubt the diagnosis of malignant tumor and are afraid and unwilling to believe. Care methods: It is not necessary to ask the patient to face the reality prematurely, and it is not necessary to correct his/her behavior as an outsider, but to accompany patiently and ask the doctor to explain more about malignant tumor related knowledge. Anxiety: Anxiety is the primary psychological problem of elderly tumor patients, up to 66.7%. Care methods: The positive effect of psychological suggestion can be used to improve patients’ sense of security and satisfaction. For example, after using certain drugs or doing certain treatments, suggest to patients that their condition is stabilizing and gradually improving, so as to reassure them. Fear: Fear is a common psychological reaction of malignant tumor patients. Common fears of cancer include fear of disease unknown, fear of pain, fear of separation from loved ones, etc. Care methods: Research shows that more than 80% of patients are willing to know their diagnosis. Taking the initiative to tell patients the doctor’s diagnosis in a measured manner, while clearly pointing out that cancer is no longer incurable and combining with some actual cases of successful cures, can alleviate patients’ fear. Depression: Due to the long-term torture of the disease or the increasing cost of treatment, patients are prone to depression and despair, and even suicidal thoughts. Care methods: Family members should avoid pessimistic language and excessive sadness in front of the patient, while soothing music can be played daily to divert the patient’s attention.