Wake up feeling stuffy and blocked chest should be considered for a variety of reasons: first, should consider whether there is the possibility of myocardial ischemia, usually combined with blood pressure, blood sugar, lipid abnormalities and other underlying diseases, can be judged by doing electrocardiogram or plate exercise electrocardiogram to observe whether there are dynamic changes in the electrocardiogram; second, may be gastroesophageal reflux, if there is gastritis, it is easy to lie down in the position of gastroesophageal reflux leading to Esophageal spasm and such symptoms; third, is not sleeping position caused by chest and intercostal muscle pressure, which can also appear to wake up feeling very stuffy chest, very blocked symptoms. It is recommended to go to the hospital for a comprehensive examination, and then do targeted treatment according to the examination results.