There is a difference between imported and domestic azithromycin, mainly in price, manufacturer and indications. 1. Different price: imported azithromycin price may be more expensive, domestic may be slightly cheaper. 2. Different manufacturers: imported azithromycin manufacturers are in foreign countries, while domestic manufacturers are in the country. 3. Different adaptability: some patients may have stronger adaptability to imported or domestic azithromycin. The situation needs to be analyzed with the specific situation of the patient. There is no obvious difference between imported and domestic azithromycin in terms of clinical application, drug metabolism and adverse reactions, but patients need to follow the doctor’s instructions.