Enlarged inguinal lymph nodes may cause symptoms of thigh pain. Enlarged inguinal lymph nodes may be caused by lymphadenitis, lymph node tuberculosis and lymphoma, etc. When the inguinal lymph node enlargement is more serious, it may lead to peripheral nerve compression, which may hinder the venous return, thus causing thigh pain. The patient may also be accompanied by lymph node pressure and pain. Thigh pain can also be caused by a buildup of lactic acid from walking for too long. Localized tissue damage caused by pressure or impact on the thigh root can also cause thigh root pain. In addition, when a herniated disc causes pressure on the peripheral nerves, it can also cause pain in the thigh root. Long-term thigh root pain symptoms, should be timely to the hospital examination and treatment, so as not to delay the condition.