The preferred antibiotics for mycoplasma pneumonia are macrolides, including the traditional erythromycin, but also the new macrolides, such as roxithromycin and azithromycin. For patients who are not sensitive to macrolides, respiratory quinolones are also available for treatment, mainly including levofloxacin, moxifloxacin, etc. In the treatment, it should be noted that cephalosporins and penicillins are ineffective for mycoplasma infections because the targets of such antibiotics are the cell walls of the pathogens, which are pathogens without cell walls. So in mycoplasma infection, you can choose macrolide antibiotics or respiratory quinolone antibiotics, but the first choice is macrolide antibiotics. However, it should be noted that the resistance rate of Mycoplasma pneumoniae to macrolide antibiotics is relatively high in China at present, so it is important to proceed carefully when choosing the medication, closely observe the patient’s status and adjust the treatment in time.