The most obvious difference between chronic colitis and colon cancer includes four aspects: etiology, clinical manifestations, colonoscopy findings and pathology. 1. Etiology: chronic colitis is a kind of chronic inflammation caused by immune factors; colon cancer is cancer caused by abnormal cell proliferation. 2. Clinical manifestations: chronic colitis usually manifests symptoms such as abdominal pain, change of bowel habit, discharge of mucus and blood stools, etc.; colon cancer usually manifests black stools and blood in stools, and prolonged bleeding will lead to anemia. 3. Colonoscopy: chronic colitis usually shows disturbed arrangement of mucous membrane of intestinal wall, and blood vessels are clearly visible; colon cancer can see erosion and ulceration, usually there is dirt at the bottom of ulcers, and the edges of ulcers are irregular. 4. Pathology: colitis usually has a large number of inflammatory cells infiltrating in the intestinal wall; colon cancer can see heterogeneous tumor cells. If there are changes in bowel habit, constipation, diarrhea, abdominal pain, etc., go to the hospital in time, and standardize the treatment under the guidance of professional doctors. Do early detection, early diagnosis and early treatment.