Pimples between the eyebrows, or acne between the eyebrows, can be treated by topical or oral medication, red and blue light irradiation, and so on. 1. Topical medication: can be applied by using clindamycin gel or vinpocetine ointment under a doctor’s supervision. In addition, it can also be regulated through the use of fusidic acid cream or peroxybenzoyl gel and so on. 2. Oral medication: If the symptoms are more serious, you can also take oral isotretinoin and minocycline, which can inhibit hyperkeratosis of the skin and inhibit bacterial reproduction, thus helping the treatment of acne between eyebrows. 3. Red and blue light irradiation: It can play the role of sterilization and anti-inflammatory, and stimulate the growth of collagen in the skin, thus helping to treat acne. If acne between the eyebrows does not go away, it is recommended that you seek medical attention and follow the doctor’s instructions for examination and treatment, rather than using your own medication.